New or worsening peripheral neuropathy may possibly require a lessened dose or altered dose agenda (see Dosage Modification)

fluconazole will enhance the amount or effect of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

fedratinib will improve the degree or impact of bortezomib by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. Modify dose of medication which are CYP2C19 substrates as vital.

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rifabutin will reduce the extent or influence of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

Explain to your overall health care Specialist that you'll be using bortezomib prior to possessing any immunizations/vaccinations. Steer clear of contact with Individuals who have recently been given Are living vaccines (which include flu vaccine inhaled through the nose).

Ahead of making use of this medication, inform your medical doctor or pharmacist If you're allergic to it; or When you have some other allergies. This merchandise may possibly have inactive ingredients (for instance boron, mannitol), which could result in allergic reactions or other problems. Check with your pharmacist for more aspects.

secobarbital will reduce the level or effect of bortezomib by influencing 3'-cGAMP sodium hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

apalutamide will lower the level or outcome of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a strong CYP3A4 inducer, with medications which can be CYP3A4 substrates may lead to lower publicity to these drugs.

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eslicarbazepine acetate will raise the stage or effect of bortezomib by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Watch.

apalutamide will reduce the extent or impact of bortezomib by influencing hepatic enzyme CYP2C19 metabolism. Steer clear of or Use Alternate Drug. Coadministration of apalutamide, a solid CYP2C19 inducer, with medicine that happen Urolithin A to be CYP2C19 substrates may lead to decrease exposure to those medicines.

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erythromycin stearate will boost the level or impact of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.